Metabolomics And Proteomics

Metabolomics And Proteomics

Question:

Task:

Design a study that would produce the most comprehensive and useful dataset, referencing the relevant literature. The methodology MUST be tailored for the specific problem, NOT a list of generic methods, and use the most up to date techniques and instrumentation available.

  • Sample preparation methods.
  • Fractionation methods.
  • Analysis (mass spectrometry) methods.
  • Bioinformatic analysis methods.

Review, analyse, interpret, critically evaluate and appropriately communicate the findings of published literature in proteomics relevant to the chosen topic.

Appropriate, recent references from the literature.
Logical argument based on fact and examples in the literature. * You MUST CRITICALLY EVALUATE the literature using knowledge you have gained throughout the subject and from other sources (Ability and motivation for continued intellectual development).
What are the advantages of the chosen methodology and is the methodologies current (Disciplinary knowledge and its appropriate application, An Inquiry-oriented approach, Initiative and innovative ability, Communication skills)?
What specific information will the chosen methodology provide for the specific sample/problem that other methods won’t (Disciplinary knowledge and its appropriate application, an Inquiry-oriented approach, Professional skills and their appropriate application, Initiative and innovative ability, Communication skills)?
What are the disadvantages of the chosen methodology (Disciplinary knowledge and its appropriate application, An Inquiry-oriented approach, Professional skills and their appropriate application, Initiative and innovative ability, Communication skills)?
Briefly mention the alternatives and the complementary information they would provide that the chosen method won’t (Disciplinary knowledge and its appropriate application, An Inquiry-oriented approach, Professional skills and their appropriate application, Initiative and innovative ability, Communication skills)?
Most importantly, ensure that you keep focused on the sample/subject/problem and write in that context, NOT generically.

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